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肺癌居癌症发病的首位,其发病率逐年上升,对人类健康造成极大的威胁,因此早期诊断肺癌并给予及时的治疗显得尤为重要。近年来,分子代谢显像技术~(18)氟-脱氧葡萄糖-PET/CT(~(18)F-FDG PET/CT)广泛应用于临床,对于恶性病变的诊断有着其他影像手段不可替代的作用,但是由于~(18)F-FDG(~(18)F标记的氟脱氧葡萄糖)不是肿瘤特异性显像剂,出现假阳性与假阴性的情况甚多。本文综述~(18)F-FDG PET/CT在肺癌应用中出现假阳性与假阴性的主要表现以及主要原因。
Lung cancer ranks first in the incidence of cancer, the incidence increased year by year, pose a great threat to human health, early diagnosis of lung cancer and give timely treatment is particularly important. In recent years, molecular metabolic imaging technique ~ (18) fluorodeoxyglucose-PET / CT (~ (18) F-FDG PET / CT) has been widely used in clinic and has an irreplaceable role in the diagnosis of malignant lesions However, due to the fact that ~ (18) F-FDG (~ (18) F-labeled fluorodeoxyglucose) is not a tumor-specific imaging agent, there are many false positives and false negatives. This review summarizes the main manifestations and main causes of ~ (18) F-FDG PET / CT in patients with lung cancer that have false positives and false negatives.