目的观察射频热疗联合全身化疗治疗晚期胃肠道肿瘤的近期疗效及症状改善情况。方法于2003年7月至2005年6月对50例晚期胃肠道肿瘤不能手术或术后复发、转移的患者,给予全身化疗同时予局部热疗,每个周期化疗3～5 d,期间给予射频热疗2～3次,每次1 h,2次间隔时间为48 h。所有患者完成化疗3～6个周期,热疗6～16次。其中胃癌24例,肠癌26例。结果 50例患者中有效率为38%,症状缓解率为46%。结论射频热疗联合化疗在晚期胃肠道肿瘤的综合治疗中对改善症状、提高生活质量、控制肿瘤有一定价值。 Objective To observe the short-term curative effect and symptom improvement of radiotherapy combined with systemic chemotherapy for advanced gastrointestinal cancer. Methods From July 2003 to June 2005, 50 patients with advanced gastrointestinal cancer who could not be operated or who had recurrence and metastasis were treated with systemic chemotherapy combined with local hyperthermia. Each cycle of chemotherapy was given 3 to 5 days. RF hyperthermia 2 to 3 times, each 1 h, 2 times interval of 48 h. All patients completed 3 to 6 cycles of chemotherapy, hyperthermia 6 to 16 times. 24 cases of gastric cancer, 26 cases of intestinal cancer. Results In 50 patients, the effective rate was 38% and the symptom relief rate was 46%. Conclusion Combined radiofrequency thermotherapy and chemotherapy in the treatment of advanced gastrointestinal cancer have some value in improving symptoms, improving quality of life and controlling tumors.