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目的:评价三子平喘颗粒用于儿童喘息性呼吸道感染的临床疗效。方法:将50例呼吸道感染伴有喘息的患儿随机分为对照组和治疗组。对照组采用常规西医治疗(抗生素、抗病毒、雾化吸入、以及糖皮质激素类药物及必要的支持对症治疗),治疗组在对照组的基础上给予三子平喘颗粒口服,疗程7 d,治疗后评价临床疗效。结果:两组治疗前后比较均疗效显著,治疗组在咳嗽,咳痰,肺部体征各指标疗效、症状综合评分改善程度以及总有效率与对照组比较差异无统计学意义,但在治疗5 d,7 d时的气促喘息的改善上治疗组优于对照组[(评分分别为(0.28±0.84)vs(0.92±0.57)分,(0.08±0.28)vs(0.32±0.56)分],(P<0.05)。结论:在西医常规治疗基础上加用三子平喘颗粒治疗儿童喘息性呼吸道感染,可有效缓解气促喘息症状,治疗效果较单纯使用西药更佳,值得临床推广应用。
Objective: To evaluate the clinical efficacy of Sanzi Pingchuan Granule in children with wheezy respiratory infection. Methods: 50 cases of respiratory tract infection with wheezing were randomly divided into control group and treatment group. The control group received routine Western medical treatment (antibiotics, antiviral, inhalation, and glucocorticoid drugs and the necessary symptomatic treatment of symptomatic treatment), the treatment group on the basis of the control group was given Sanzi Pingchuan granules oral treatment for 7 days, treatment After evaluation of clinical efficacy. Results: The curative effect of the two groups were significant before and after treatment. There was no significant difference between the two groups in cough, sputum aspiration, the indexes of lung signs, the improvement of symptom score and the total effective rate as compared with the control group. However, (P <0.28 ± 0.84 vs 0.92 ± 0.57, respectively, (0.08 ± 0.28) vs (0.32 ± 0.56) vs (0.32 ± 0.56), P <0.05] P <0.05) .Conclusion: The San Zi Ping Chuan Granule can effectively relieve the wheezing and wheezing symptoms in children based on routine treatment of western medicine, and the treatment effect is better than western medicine alone, which is worthy of clinical application.