论文部分内容阅读
目的探讨银杏叶片对急性脑梗死患者阿司匹林抵抗的影响。方法将158例急性脑梗死患者,其中筛出阿司匹林抵抗(AR)和阿司匹林半抵抗(ASR)患者96例,随机分为观察组和对照组,每组48例,两组均服用阿司匹林100mg/d,共服用4周。对照组给予常规治疗,观察组在常规治疗的同时加用银杏叶片2片,日三次口服。4周后进行血小板聚集率和血常规检测,评价阿司匹林抵抗的发生率。结果观察组的急性脑梗死患者血小板聚集率低于对照组,二者有统计学意义(P<0.05)。结论银杏叶片可降低阿司匹林抵抗患者的血小板聚集率,提示临床工作中应充分重视,积极监测血小板聚集率,应用药物积极防治阿司匹林抵抗,避免或减少血栓疾病的发生。
Objective To investigate the effect of ginkgo leaf on aspirin resistance in patients with acute cerebral infarction. Methods A total of 158 patients with acute cerebral infarction, including 96 aspirin-resistant (AR) and aspirin-resistant (ASR) patients, were randomly divided into observation group and control group, with 48 patients in each group. All patients were given aspirin 100mg / d For a total of 4 weeks. Control group given conventional treatment, observation group in the conventional treatment plus ginkgo leaves 2 tablets, three times daily oral. Four weeks later, platelet aggregation rate and blood routine test were performed to evaluate the incidence of aspirin resistance. Results The platelet aggregation rate in the observation group was lower than that in the control group, both of which were statistically significant (P <0.05). Conclusion Ginkgo biloba can reduce the platelet aggregation rate in patients with aspirin resistance, suggesting that full attention should be paid in clinical work. Active monitoring of platelet aggregation rate should be used to prevent aspirin resistance and avoid or reduce the incidence of thrombosis.