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硒卡拉胶(k-Selenocarrageenan)是天然硫酸酯多糖,经硒取代制成的硒有机化合物,较之于无机硒毒性低、生物利用度高、生理增益效应大。近年来对其药理作用的研究日趋深入,临床应用日趋广泛。1 药理作用1.1 保护细胞结构当细胞膜流动性降低时,膜蛋白更易暴露于水溶液并对酶活性产生影响,饱和脂肪酸增加的衰老红细胞,膜流动性降低,硒卡拉胶可显著降低大鼠红细胞膜荧光偏振度,即可显著提高细胞膜流动性(P<0.05);红细胞膜封闭度随着细胞的老化而失去,成熟红细胞膜封闭度约为
Selenocarrageenan is a naturally-occurring polysaccharide of selenocarrageenan, which is a selenium organic compound made by selenium substitution. It has lower bioavailability and physiological benefits than inorganic selenium. In recent years, the research of its pharmacological effects has become more and more in-depth, and its clinical application is increasingly widespread. 1 Pharmacological effects 1.1 Protection of cell structure When the membrane fluidity decreases, the membrane protein is more exposed to aqueous solution and have an impact on the enzyme activity, saturated fatty acids increased senescence erythrocytes, membrane fluidity decreased, selenium carrageenan can significantly reduce rat erythrocyte membrane fluorescence Degree of polarization, can significantly improve the fluidity of the membrane (P <0.05); the membrane of the erythrocyte membrane closure with the aging of the cells lost, the closedness of the mature erythrocyte membrane is about