氨吡酮为一新型正性肌力药,它抑制磷酸二酯酶从而增加心肌的环磷酸腺苷(cAMP),而不是刺激β肾上腺素能受体,它增加心收缩力而不增加心肌氧耗。这些特点较适用于缺血性心脏病和左室功能差的病人。这些病人的β受体密度减低,不宜使用显著增加心肌氧耗的正性肌力药。 6例左室收缩功能严重减退的病人接受 Praziquantel, a novel inotropic drug that inhibits phosphodiesterase and thereby increases cAMP in the myocardium rather than stimulating the beta adrenergic receptor, increases cardiac contractility without increasing myocardial oxygen Consumption These characteristics are more suitable for ischemic heart disease and poor left ventricular function in patients. These patients reduce the beta receptor density should not be used to significantly increase myocardial oxygen consumption inotropic drugs. Six patients with severe loss of left ventricular systolic function were accepted