肝性脑病(hepatic encephalopathy,HE)是由严重肝病引起的,以代谢紊乱为基础的中枢神经系统功能失调综合征,其主要临床表现为意识障碍、行为失常和昏迷。 大部分HE是由各型肝硬化引起的,暴发性肝功能衰竭、门-体分流手术、原发性肝癌、妊娠期急性脂肪肝等均可引起HE。HE的发生严重影响肝病患者的生活质量,甚至危及生命,因此对其治疗方法的探索一直是临床医师十分重 Hepatic encephalopathy (HE) is a central nervous system dysfunction syndrome caused by severe liver disease and based on metabolic disorders. Its main clinical manifestations are disturbance of consciousness, behavioral disorders and coma. Most HE is caused by various types of cirrhosis, fulminant hepatic failure, portal-to-body shunt surgery, primary liver cancer, acute fatty liver during pregnancy can cause HE. The occurrence of HE seriously affects the quality of life of patients with liver disease, and even life-threatening, so the exploration of its treatment has been clinically very heavy