论文部分内容阅读
对2003年8月至2005年12月因骨和/或关节疼痛麻木在四川大学华西医院门诊及住院1 207例男性经X线检查判断无骨质增生482人,采用法国DMS公司生产的Challenger双能X线骨密度仪测定L2～4正位骨密度,记录其身高、体重(计算体重指数)、症状、并发症、运动、吸烟等基线状况;测定L2～4骨密度,明确是否骨质疏松;用t检验或2检验比较骨质疏松组和无骨质疏松组基线状况,用逻辑回归分析实验对象中各种可能影响骨质疏松的因素与骨质疏松的相关性。结果显示:骨质疏松和无骨质疏松两组比较:体重指数、运动情况和吸烟比例有显著差异;高血压和糖尿病患病比例、年龄无明显差异;根据多因素分析,体重指数和吸烟是骨质疏松的危险因素,运动是骨质疏松的保护因素。BMI每增加一个单位,男性发生骨质疏松的风险增加0.654倍(P=0.004)。因此,我们认为体重指数是男性骨质疏松的危险因素,可能与体脂分布不同有关。
From Aug. 2003 to Dec. 2005, 1 207 men were diagnosed as having no bone hyperplasia by X-ray examination of outpatients and hospitalized in West China Hospital of Sichuan University from numbness of bone and / or joints in December 2003. Using Challenger bis The BMD of L2 ~ 4 was measured by X-ray absorptiometry. Baseline conditions such as height and weight (calculated body mass index), symptoms, complications, exercise and smoking were recorded. L2 ~ 4 BMD was measured to determine whether osteoporosis . The baseline status of osteoporosis group and no osteoporosis group were compared by t test or 2 test. Logistic regression analysis was used to analyze the correlation between various factors that may affect osteoporosis and osteoporosis in the experimental subjects. The results showed that there were significant differences in body mass index, exercise status and smoking ratio between the two groups; there was no significant difference in the prevalence of hypertension and diabetes among the two groups. According to multivariate analysis, BMI and smoking were Osteoporosis risk factors, exercise is a protective factor of osteoporosis. For each unit increase in BMI, men have a 0.654-fold increased risk of developing osteoporosis (P = 0.004). Therefore, we believe that body mass index is a risk factor for osteoporosis in males, which may be related to the different body fat distribution.