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目的:通过回顾性分析57例围生期下肢静脉血栓患者的临床资料,总结围生期下肢深静脉血栓形成的治疗方法。方法:整理分析本院2001年12月至2014年12月57例围生期下肢静脉血栓患者的临床资料,系统分析其年龄、发病时间、临床表现及特征、影像学检查及其他辅助检查特点。结果:围生期下肢静脉血栓好发于20~30岁(57.89%);发生于产褥期深静脉血栓(DVT)有42例(73.68%);左侧下肢DVT有31例(54.38%),主要症状为患肢肿胀91.22%、疼痛85.96%、行动不便50.87%;全部均可出现彩色多普勒超声成像异常,绝大多数D-二聚体阳性(92.98%)及血纤维蛋白原升高(98.24%)、APTT异常(59.62%)。结论:对围生期血栓疾病高危人群进行干预,以减少围生期血栓性疾病的发生;对围生期下肢静脉血栓患者及时采取以低分子肝素为主的系统抗凝治疗。
Objective: To retrospectively analyze the clinical data of 57 patients with perinatal venous thrombosis of the lower extremity and summarize the treatment of perinatal lower extremity deep vein thrombosis. Methods: The clinical data of 57 patients with peripheral venous thrombosis in the perinatal period from December 2001 to December 2014 were analyzed and analyzed. The characteristics of age, onset time, clinical manifestations and features, imaging examination and other auxiliary examinations were systematically analyzed. Results: Peripheral venous thrombosis of the lower extremities occurred in 20-30 years old (57.89%); in the puerperal DVT 42 cases (73.68%); left lower extremity DVT in 31 cases (54.38%), mainly Symptoms were swelling of the limb 91.22%, pain 85.96%, motion sickness 50.87%; all can occur color Doppler ultrasound imaging, the vast majority of D-dimer-positive (92.98%) and fibrinogen ( 98.24%), abnormal APTT (59.62%). Conclusion: Perinatal thrombosis disease at high risk groups intervention, in order to reduce the incidence of perinatal thrombotic diseases; Perinatal venous thrombosis in patients with low molecular weight heparin-based system anticoagulant therapy.