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用改良的静脉留置针将地鼠气管腹侧面粘膜刮除，经时取材，用光、电镜观察气管上皮修复过程中粘液分泌细胞的超微结构，以探索粘液分泌细胞在气管上皮修复中的作用。结果：损伤后６ｈ边缘部上皮细胞开始增殖变为扁平状并向损伤面爬行；２４ｈ覆盖损伤面。电镜下这些细胞表面无纤毛或仅有少量微绒毛，胞浆内有大小不等散在的粘液颗粒和较多的粗面内质网，与光镜下含有细小或融合性的ＰＡＳ（＋）颗粒相一致。３６ｈ后，损伤面由３～５层表皮样化生细胞构成，核周出现蛋白丝状物围绕，部分胞浆内仍有少量粘液颗粒。７２ｈ后，细胞出现短而细的纤毛或出现较多的粘液空泡。２周后恢复正常结构。认为：粘液分泌细胞不是终末细胞，而是损伤后参与修复的主要细胞之一。
The modified venous catheter was used to remove the mucosa of the gland trachea ventral mucosa. The ultrastructure of mucus-secreting cells during tracheal epithelial repair was observed by light and electron microscope to explore the role of mucous secreting cells in tracheal epithelial repair . Results: The epithelial cells began to proliferate and became flat at 6h after injury, and then spread to the lesion surface. Under the electron microscope, these cells had no cilia or only a few microvilli on the surface. The cytoplasm had scattered mucus particles and more rough endoplasmic reticulum, which contained fine or fusional PAS (+) particles under light microscope Consistent. After 36h, the lesion surface consisted of 3 to 5 epidermis-like metaplastic cells, surrounded by protein filaments around the peri-nucleus, and some mucus particles remained in some cytoplasm. After 72h, the cells appeared short and thin cilia or more mucus vacuoles. After 2 weeks to restore normal structure. That: mucus-secreting cells are not terminal cells, but one of the main cells involved in repair after injury.