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目的探讨准分子激光上皮瓣下角膜磨镶术(LASEK)矫治近视的优缺点。方法选择双眼近视程度相近患者,双眼同时手术,一眼行准分子激光角膜切削术(PRK),另一眼行LASEK,进行前瞻性自身对照研究,将PRK眼作为对照组,LASEK眼作为治疗组,术后随访6个月以上。结果两组术后疼痛程度无明显差异,角膜上皮下雾状混浊(Haze)的发生率在1、3个月时,LASEK组较PRK组明显低、程度轻,6个月时两组比较无明显差异;LASEK组的视力恢复较PRK组更快、更佳。结论LASEK治疗近视,是一种安全、有效的方法,其Haze发生率低且程度轻,视力恢复更快、更佳。
Objective To investigate the advantages and disadvantages of laser subepithelial keratomileusis (LASEK) in the treatment of myopia. Methods The patients with similar degree of bilateral myopia were selected. Simultaneous operation was performed in both eyes. One eye underwent excimer laser keratectomy (PRK) and the other underwent LASEK. A prospective self-controlled study was conducted. PRK eyes were used as control group and LASEK eyes as treatment group. Follow-up more than 6 months. Results There was no significant difference in postoperative pain between the two groups. The incidence of haze in the corneal epithelium was significantly lower at 1 and 3 months than that in the PRK group, and was less in the LASEK group at 6 months Significant difference; LASEK group visual acuity faster and better than the PRK group. Conclusions LASEK is a safe and effective method for the treatment of myopia. The incidence of Haze is low and mild, and visual acuity is recovered faster and better.