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目的:分析联合应用甲硝唑及头孢氨苄对慢性牙周炎(CP)的临床疗效。方法:按照入院顺序奇偶法将我院2015年1月-2015年11月收治的86例CP患者随机分为两组,即对照组和观察组,各43例。对照组应用甲硝唑治疗,观察组联合应用甲硝唑及头孢氨苄治疗;治疗2周后,比较两组出血指数、菌斑指数、附着丧失、牙周探诊深度以及总有效率。结果 :治疗2周后,观察组总有效率达100.00%,显著高于对照组86.05%(P<0.05);观察组出血指数、菌斑指数、附着丧失、牙周探诊深度等指标均显著优于对照组(P<0.05)。结论 :与应用甲硝唑单药相比,联合应用甲硝唑及头孢氨苄治疗CP的临床疗效更佳。
Objective: To analyze the clinical effect of combined application of metronidazole and cephalexin on chronic periodontitis (CP). Methods: Eighty-six patients with CP who were admitted to our hospital from January 2015 to November 2015 were randomly divided into two groups (control group and observation group, 43 cases in each). The control group was treated with metronidazole, and the observation group was treated with metronidazole and cephalexin. After 2 weeks of treatment, bleeding index, plaque index, loss of attachment, depth of probing and total effective rate were compared. Results: After 2 weeks of treatment, the total effective rate in the observation group was 100.00%, which was significantly higher than that in the control group (86.05%, P <0.05). Bleeding index, plaque index, loss of attachment, depth of periodontal exploration were all significant Better than the control group (P <0.05). Conclusion: Compared with the application of metronidazole monotherapy, the combination of metronidazole and cephalexin in the treatment of CP clinical effect is better.