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目的探讨妊娠期糖尿病(GDM)孕妇的新生儿血清胰岛素水平与出生体质量的关系。方法对38例GDM孕妇的新生儿进行血清胰岛素水平测定,与正常孕妇的新生儿相比较,进行血清胰岛素水平与出生体质量的相关性分析。结果观察组血清胰岛素水平明显高于对照组,有显著差异,观察组血清胰岛素水平与出生体质量的相关系数为γ=0.558,P=0.007。结论GDM孕妇的新生儿生后3d血糖正常后仍存在高胰岛素血症,新生儿的体质量与高胰岛素血症呈显著相关性。
Objective To investigate the relationship between neonatal serum insulin levels and birth weight in pregnant women with gestational diabetes mellitus (GDM). Methods Serum insulin levels were measured in 38 neonates with GDM and compared with those of normal pregnant women. The correlation between serum insulin level and birth weight was analyzed. Results The level of serum insulin in the observation group was significantly higher than that in the control group. The correlation coefficient between serum insulin level and birth weight was γ = 0.558, P = 0.007. Conclusion GDM pregnant women still have hyperinsulinemia after birth, and there is a significant correlation between neonatal body weight and hyperinsulinemia.