随着围产医学的发展,窒息等严重威胁围产儿生命的疾病发生率逐渐下降,而早产已成为导致围产儿发病及死亡的首要原因〔1〕。目前,世界上对早产儿及其相关并发症的研究已成为热点,其中,早产儿视网膜病(Retinopathy of Prem atu-rity,ROP)是导致小儿失明的重要原因〔2〕,严重影响? With the development of perinatal medicine, the incidence of diseases such as asphyxiation and other serious threats to the lives of perinatal children gradually declines, and premature labor has become the leading cause of perinatal morbidity and mortality [1]. At present, the research on premature infants and their related complications has become a hot spot in the world. Among them, Retinopathy of Premraine (ROP) is a major cause of blindness in children [2].