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本文观察了甲基黄酮醇胺（ＭＦＡ）对麻醉犬冠脉血流和心功能的影响。静脉注射５ｍｇ／ｋｇ可降低血压和心率，并增加主动脉流量和冠脉流量，但对左室收缩压（ＬＶＳＰ）、左室舒张末期压（ＬＶＥＤＰ）及左室收缩压、舒张压变化最大速率（±ｄｐ／ｄｔ＿ｍａｘ）无明显影响；ＭＦＡ降低心肌耗氧指数、总外周阻力和冠脉阻力，并增加心搏出量，作用时间超过３０ｍｉｎ。研究表明ＭＦＡ可望成为防治缺血性心脏病的有效药物。
In this paper, we observed the effects of methylflavonolamine (MFA) on coronary blood flow and cardiac function in anesthetized dogs. Intravenous injection of 5mg / kg can reduce blood pressure and heart rate, and increase aortic flow and coronary flow, but the left ventricular systolic pressure (LVSP), left ventricular end-diastolic pressure (LVEDP) and left ventricular systolic pressure, diastolic blood pressure changes the maximum rate (± dp / dt_max); MFA decreased myocardial oxygen consumption index, total peripheral resistance and coronary resistance, and increased cardiac output, the role of time more than 30min. Studies have shown that MFA is expected to become an effective drug for the prevention and treatment of ischemic heart disease.