论文部分内容阅读
目的探索孕前危险因素对低出生体重(Low Birth Weight,LBW)的影响。方法采用多阶段随机整群抽样方法抽取4个县区40个乡的2 011名拟孕育龄妇女,开展孕前健康检查,随访观察妊娠结局。数据资料采用EpiData 3.02双录入,SAS9.3进行数据分析。结果共有767名怀孕,有16名体重低于2 500g,LBW发生率为2.08%,7例早产儿。有生殖道感染史的妇女LBW发生风险是无感染者的4.56倍(95%CI:1.333~15.631);有孕早期自然流产史的妇女LBW发生风险为孕早期无自然流产史的3.0倍(95%CI:1.01~8.92)。BMI<18.5kg/m2的妇女其LBW发生率高于正常BMI妇女,BMI>25kg/m2的妇女LBW发生率低于正常体型妇女;血红蛋白水平异常(增高或降低)的妇女LBW的发生率高于正常血红蛋白(Hb)水平妇女;LBW的发生率与妇女孕前空腹血糖水平负相关(P<0.05)。结论母亲孕前有生殖道感染史、孕早期自然流产史可能增加其胎儿低体重发生风险。
Objective To explore the influence of pre-pregnancy risk factors on low birth weight (LBW). Methods A total of 2 011 pregnant women of childbearing age from 40 townships in 4 counties and districts were selected by multistage randomized cluster sampling to carry out preconception health examination. The pregnancy outcome was followed up. Data using EpiData 3.02 double entry, SAS9.3 for data analysis. Results A total of 767 pregnancies, 16 patients weighing less than 2500g, LBW incidence of 2.08%, 7 cases of premature children. Women with a history of genital tract infection were 4.56 times more likely to develop LBW (95% CI: 1.333 to 15.631) than those without infection; women with a history of first trimester LBW were at least 3.0 times as likely to develop LBW % CI: 1.01 ~ 8.92). Women with a BMI of <18.5 kg / m2 had a higher prevalence of LBW than women with a normal BMI, women with a BMI> 25 kg / m2 had a lower incidence of LBW than women with normal body size, and LBW with an abnormal (increased or decreased) hemoglobin level The incidence of LBW was negatively correlated with the level of fasting blood glucose before pregnancy (P <0.05) in women with normal hemoglobin (Hb) level. Conclusion The mother had a history of genital tract infection before pregnancy and the history of spontaneous abortion may increase the risk of low birth weight.