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46例确诊为急性心肌梗塞(AMI)的患者,随机分为镁(Mg~(2+))治疗组(n=23)和对照组(n=23)。治疗组入院后加用2.08mmol/L(25％)硫酸镁30ml和0.56mmol/L(10％)葡萄糖500ml缓慢静滴,维持24h。以带有微机存贮心电信号的监护仪进行监护,给药前后测定血清Mg~(2+)及其它电解质含量。结果:治疗组严重室性心律失常的发生率显著低于对照组(P<0.05);治疗过程中未引起患者血压明显波动及ECG间期异常,也未见其它副作用;治疗前后血清Mg~(2+)及其它电解质平均含量均在正常范围。
Forty-six patients with acute myocardial infarction (AMI) were randomly divided into magnesium (Mg 2+) group (n = 23) and control group (n = 23). Treatment group after admission plus 2.08mmol / L (25%) magnesium sulfate 30ml and 0.56mmol / L (10%) glucose 500ml slow intravenous infusion for 24h. Monitoring was performed with a monitor with a computerized ECG signal. Serum Mg 2+ and other electrolytes were measured before and after administration. Results: The incidence of severe ventricular arrhythmia in the treatment group was significantly lower than that in the control group (P <0.05). No significant fluctuations in blood pressure and ECG interval were observed in the treatment group, and no other side effects were observed. Before and after treatment, 2+) and other electrolytes were in the normal range.