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目的:了解我院药品不良反应的发生规律及特点,促进临床合理用药。方法:对我院2007年报告的227例药品不良反应,利用Microsoft Excel电子表格进行归类统计和分析评价。结果:227例报告中女性多于男性;中、老年患者比例较高;给药途径以静脉滴注致不良反应最常见;抗微生物感染药发生例数最多;严重不良反应7例;最常见的不良反应是皮肤粘膜系统损害(85例),其次为神经系统损害(66例)。结论:继续加强不良反应监测和对不良反应相关知识的宣传,重视对临床表现隐匿的不良反应的监测,促进合理用药,尽量减少不良反应的发生。
Objective: To understand the incidence of adverse drug reactions and characteristics of our hospital to promote clinical rational use of drugs. Methods: 227 cases of adverse drug reactions reported in our hospital in 2007 were classified and analyzed by Microsoft Excel spreadsheet. Results: There were more women than men in 227 cases. The proportion of middle-aged and elderly patients was higher. The most common adverse reactions were intravenous drip. The most frequent cases were antimicrobial infections. The most serious adverse reactions were in 7 cases. The most common Adverse effects were mucocutaneous system damage (85 cases), followed by nervous system damage (66 cases). CONCLUSION: We will continue to strengthen the monitoring of adverse reactions and the publicity of the knowledge about adverse reactions, pay attention to the monitoring of adverse reactions hidden in clinical manifestations, promote the rational use of drugs, and minimize the occurrence of adverse reactions.