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作者测定２７例健康人及５７例慢性肾功能不全患者血浆脂质过氧化物含量、红细胞超氧化物歧化酶的话性，经统计学处理，５７例慢性肾功能不全患者血浆ＬＰＯ含量较健康人有显著性差异，而红细胞ＳＯＤ活性随肾功能恶化，ＢＵＮ、Ｃｒ上升而下降，提示慢性肾功能不全的发病及病程进展与自由基损伤有密切关系。
The authors measured plasma lipid peroxidation levels and erythrocyte superoxide dismutase in 27 healthy subjects and 57 patients with chronic renal insufficiency. Statistical analysis showed that LPO levels in 57 patients with chronic renal insufficiency were significantly higher than those in healthy individuals Significant differences, while the activity of erythrocyte SOD with the deterioration of renal function, BUN, Cr increased and decreased, suggesting that the pathogenesis and progression of chronic renal insufficiency and free radical damage are closely related.