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骨骼肌对缺血耐受性的概念,建立在对截肢、断肢再植和应用止血带后血循环暂时性受阻的研究基础之上。作者通过研究认为,以往的概念不适用于由急性高压性骨筋膜间隙综合征引起的缺血。作者研究了骨骼肌对应用止血带(缺血)和急性骨筋膜间隙综合征(缺血和压力)的不同反应。用狗做实验。在全麻(用氮氧混合氟烷吸入麻醉)下,放置中心静脉压导管,调节通气和吸入的氧流量,使PO_2,PCO_2、pH维持在正常范围之内。对止血带组5只狗用手挤压一侧后肢驱血后,大腿部绕一儿科用的气囊,充气至350mm
The concept of skeletal muscle tolerance to ischemia is based on a study of the temporary blockage of blood circulation following amputation, replantation of severed limbs and application of a tourniquet. The authors believe that previous concepts do not apply to ischemia caused by acute hypertonic osteoflagellar gap syndrome. The authors studied the different responses of skeletal muscle to the application of a tourniquet (ischemia) and acute compartment syndrome (ischemia and pressure). Experiment with dogs. Under general anesthesia (anesthesia with inhalation of nitrous oxide and flucloalkane), a central venous pressure catheter was placed to adjust the flow of oxygen and inhaled oxygen so that PO 2, PCO 2 and pH were maintained within the normal range. On the tourniquet group, 5 dogs squeezed their hindlimbs with their hands and expelled the blood. The thighs were inflated to 350 mm around a pediatric balloon