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人的肿瘤坏死因子(TNF)在体外能抑制骨髓造血干细胞集落形成。从而考虑再生障碍性贫血(以下简称再障)血清中有否该样因子活性,以期探讨TNF 活性与再障发病关系。材料和方法30名正常人血清采自献血员。30例再障血清来自本院住院患者(按宝鸡全国再障会议诊断标准),未分型,未经任何治疗。
Human tumor necrosis factor (TNF) inhibits bone marrow hematopoietic stem cell colony formation in vitro. To consider aplastic anemia (hereinafter referred to as aplastic anemia) whether the serum of such factor activity, in order to explore the relationship between TNF activity and aplastic anemia. Materials and Methods 30 normal human sera were collected from donors. 30 cases of aplastic anemia in our hospitalized patients (according to Baoji national aplastic anemia conference diagnostic criteria), not sub-type, without any treatment.