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大环内酯类抗生素,红霉素、克拉霉素、罗红霉素被1991年Kikuchi等首次用于治疗CS、鼻息肉及柯-陆氏术后仍有症状者,反应良好,此后报道日多。已知CS患者的纤毛摆动频率(CBF)、糖精粒传输(STT)速率减慢;一氧化氮(NO)水平是气道炎症是标记物,CS患者鼻NO水平低于健康对照组;动物实验证实红霉素可加快CBF。该作者为研究经ESS后仍有持久CS
Macrolide antibiotics, erythromycin, clarithromycin, roxithromycin was first used by Kikuchi in 1991, such as CS, nasal polyps and Ke - Lu after surgery are still symptomatic, good response, since then reported many. It is known that the ciliary beat frequency (CBF) and the rate of saccharin transport (STT) in CS patients are slowed down. The level of nitric oxide (NO) is a marker of airway inflammation and the level of nasal NO in CS patients is lower than that in healthy controls. Prove that erythromycin can speed CBF. The author still has persistent CS for the study after ESS