班氏丝虫病患者体内特异性IgE和IgG4的水平均增高。体外定量检测丝虫特异性IgE受限制,因在血清中相关的同型免疫球蛋白中它所占的比例很小,同时因为在丝虫抗原上与IgG4有相同表位而受其潜在的竞争作用,检测它的准确性不大高。为明确IgG4或者其它同型抗体对丝虫特异性IgE检测的影响,作者采用Rihet等(1992)的免 Bancroftian filariasis patients with elevated levels of specific IgE and IgG4. Quantitative detection of filarial-specific IgE in vitro is limited by its small proportion in the serum related isotype immunoglobulins and its potential competition due to the same epitope on filarial antigens as IgG4 , Its accuracy is not high detection. To clarify the effect of IgG4 or other isotype antibodies on filaggiose-specific IgE detection, the authors used Rihet et al. (1992)