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观察果糖二磷酸钠与葛根素治疗冠心病的疗效并进行比较。随机将 86例冠心病心绞痛患者分成 3组 ,果糖二磷酸钠 (FDP)组在常规治疗的基础上加用FDP10g溶于 10 0ml注射用水中静滴 ,葛根素组加用葛根素 3 0 0mg加入 10 %葡萄糖 (G·S) 5 0 0ml静滴 ,对照组用普通胰岛素 8～ 12U加入含氯化钾 1.0 g的 10 %G·S5 0 0ml中静滴。结果三组总有效率分别为 93 %、96%和 2 7% ;(FDP组和葛根素组比较P >0 .0 5 ,两组分别与对照组比较 ,均为P <0 .0 1)。心电图有改善分别为66%、73 %、15 % ,(前二者相比P >0 .0 5 ,两组分别与对照组比较P <0 .0 1)。心肌耗氧指标 (RPP =心率×收缩压 )治疗前后FDP组和葛根素组均显著下降 ,与对照组比较改善非常显著 (P <0 .0 1)。心电图中心肌缺氧程度指标 (NST和ΣST即 12导联中ST段下移导联数和ST段下移mm数之和 )各组治疗前后均有显著改善 ,唯组间差别不大。提示葛根素治疗冠心病优于果糖二磷酸钠及对照组疗法。
To observe the efficacy of sodium fructose diphosphate and puerarin in the treatment of coronary heart disease and compare. Eighty-six patients with coronary heart disease were randomly divided into three groups. FDP group was treated with FDP10g dissolved in 10ml water for injection on the basis of conventional treatment, and the Puerarin group was added with Puerarin 300mg 10% glucose (G · S) 500ml intravenous infusion, the control group with ordinary insulin 8 ~ 12U added potassium chloride 1.0g 10% G · S5 0 0ml intravenous infusion. Results The total effective rates of the three groups were 93%, 96% and 27% respectively (P> 0.05 for FDP group and puerarin group, P <0.01) . The improvement of electrocardiogram was 66%, 73%, 15% respectively (P> 0.05 for the first two groups, P <0.01 compared with the control group). Myocardial oxygen consumption index (RPP = heart rate × systolic blood pressure) before and after treatment FDP group and puerarin group were significantly decreased, compared with the control group to improve very significant (P <0.01). Electrocardiogram myocardial hypoxia index (NST and Σ ST that is the 12 lead in the ST segment down the lead and ST segment down the sum of mm number) before and after treatment were significantly improved in all groups, the only difference between groups was not. Tip puerarin treatment of coronary heart disease better than fructose diphosphate and control group therapy.