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目的:探讨不同病原体肠炎患儿血PCT、CRP的变化及其临床意义。方法:检测已经确诊的30例病毒性肠炎患儿、32例细菌性肠炎患儿的血CRP(C反应蛋白)和PCT(血降钙素原)。结果:将CRP>10mg/L、PCT>0.5Lg/L作为阳性阈值,病毒组的CRP、PCT阳性率分别为40.0%、20.0%,细菌组的CRP、PCT阳性率分别为84.4%、87.5%。细菌组明显高于病毒组(P值<0.01)。CRP诊断细菌性肠炎的准确度、特异度、敏感度、阴性预测值及阳性预测值都明显小于PCT。结论:血PCT、CRP检测对鉴别小儿肠炎的病原体有重要临床意义,而PCT检测较CRP诊断细菌性肠炎价值更高。
Objective: To investigate the changes of blood PCT and CRP in children with different pathogenic enteritis and its clinical significance. Methods: Blood CRP (C-reactive protein) and PCT (procalcitonin) were detected in 30 children with viral enteritis and 32 children with bacterial enteritis. Results: The positive rates of CRP and PCT in the virus group were 40.0% and 20.0% with CRP> 10mg / L and PCT> 0.5Lg / L respectively. The positive rates of CRP and PCT in the bacterial group were 84.4% and 87.5% . Bacterial group was significantly higher than the virus group (P value <0.01). The accuracy, specificity, sensitivity, negative predictive value and positive predictive value of CRP in diagnosing bacterial enteritis were significantly lower than those in PCT. Conclusion: The detection of blood PCT and CRP has important clinical significance for the identification of pathogens in children with enteritis. However, the PCT test is more valuable than CRP in the diagnosis of bacterial enteritis.