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目的观察吲达帕胺联合二甲双胍治疗肥胖型轻中度高血压病患者的疗效。方法 70例原发性轻中度高血压患者随机分为治疗组合对照组,治疗组给予吲达帕胺、二甲双胍片,对照组单用吲达帕胺,两组治疗前后作体重指数及高血压监测。结果两组收缩压及舒张压下降,治疗组下降更为明显,与对照组相比有统计意义(P<0.05),治疗组BMI与对照组比较有差异,有统计学意义(P<0.05)。结论吲达帕胺联合二甲双胍可明显减轻体重,更有效控制血压在理想范围内。
Objective To observe the efficacy of indapamide combined with metformin in the treatment of obese patients with mild to moderate hypertension. Methods Seventy patients with primary mild to moderate hypertension were randomly divided into treatment group and control group. Indapamide and metformin tablets were given to the treatment group and indapamide alone was given to the control group. Before and after treatment, body mass index and hypertension monitor. Results The systolic blood pressure and diastolic blood pressure decreased in both groups, and the decrease in the treatment group was more obvious than that in the control group (P <0.05). The BMI in the treatment group was significantly different from that in the control group (P <0.05) . Conclusion Indapamide combined with metformin can significantly reduce body weight, and more effectively control blood pressure in the ideal range.