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目的分析老年高血压不同心血管危险分层患者的左心室质量指数(LVMI)、舒张早期二尖瓣口峰值流速/舒张晚期二尖瓣口峰值流速(E/A)、舒张早期二尖瓣口峰值流速/二尖瓣环舒张早期运动速度(E/E’)、等容舒张时间(IVRT)、B型钠利尿肽前体(NT-pro BNP),以更好地对老年高血压患者心血管危险进行预测。方法选择急诊救治中心就诊的高血压患者共230例进行回顾性分析,对所有患者进行心血管危险分层,包括极高危组33例,低危组77例,高危组57例,中危组63例,对各组患者给予超声心动图检查,计算患者的LVMI、E/A、E/E’、IVRT,并测定不同严重程度分级患者的氨基末端NT-pro BNP水平。结果 (1)极高危组LVMI、E/E’、IVRT值最高,低危组最低,各组间对比差异均有统计学意义(P均<0.05);极高危组E/A最小,低危组最高,各组间对比差异均有统计学意义(P均<0.05)。(2)极高危组NT-pro BNP最高,低危组最低,各组间对比差异均有统计学意义(P均<0.05)。结论老年高血压不同心血管危险分层患者超声心动图检查结果及NT-pro BNP检查结果有统计学差异,利用LVMI、E/A、E/E’、IVRT、NT-pro BNP能够对高血压患者心血管风险进行预测。
Objective To analyze the changes of left ventricular mass index (LVMI), mitral valve peak early diastolic flow velocity / early diastolic mitral valve peak flow velocity (E / A), early diastolic mitral valve orifice Peak flow rate / mitral annular early diastolic velocity (E / E ’), isovolumic relaxation time (IVRT) and B-type natriuretic peptide precursor (NT-pro BNP) Predict vascular risk. METHODS: A total of 230 hypertensive patients treated at the emergency center were retrospectively analyzed. All patients were stratified in cardiovascular risk, including 33 cases of very high risk group, 77 cases of low risk group, 57 cases of high risk group, 63 cases of moderate risk group For example, echocardiography was performed on each group of patients, LVMI, E / A, E / E ’and IVRT were calculated and the levels of amino-terminal NT-pro BNP in patients with different severity grading were determined. Results (1) LVMI, E / E ’and IVRT were the highest in the extremely high risk group and the lowest in the low risk group, with significant difference between the groups (P <0.05) Group was the highest, the differences between the groups were statistically significant (P all <0.05). (2) NT-pro BNP was the highest in the extremely high risk group and lowest in the low risk group, with significant difference between the groups (all P <0.05). Conclusions Echocardiographic results and NT-pro BNP test results in patients with different cardiovascular risk stratification in elderly patients are statistically different. LVMI, E / A, E / E ’, IVRT and NT- Predict cardiovascular risk in patients.