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降钙素基因相关肽(Calcitonin gene related peptide,CGRP)是目前已知最强的舒血管物质之一。有关CGRP的研究在疾病的发生发展的联系正在受到广泛的重视。我们测定了38例患重症肺炎的新生儿治疗前后血浆中CGRP的含量,且与正常新生儿对照,并作统计学处理。现将结果报道如下。1 对象和方法1．1 对象我们所测病例均为本院新生儿病区收治的重症肺炎患儿共38例,其中男23例,女15例。入院时日龄最大为24天,最小3小时,平均12.6天。对照组为本院健康体检新生儿,共22例,肝肾功能正常,无心脑肺疾患,男11例,女11例,日龄最大22天,最小2小时,平均13.4天。
Calcitonin gene related peptide (Calcitonin gene related peptide, CGRP) is one of the strongest known vasodilators. The link between the research of CGRP and the occurrence and development of the disease is receiving more and more attention. We measured 38 cases of severe pneumonia in neonates before and after treatment of plasma CGRP levels, and compared with normal newborns, and for statistical analysis. The results are reported below. 1 Subjects and Methods 1.1 Subjects We measured cases were hospitalized neonatal ward admitted to a total of 38 cases of severe pneumonia in children, including 23 males and 15 females. Admission at the maximum age of 24 days, a minimum of 3 hours, an average of 12.6 days. The control group was a healthy newborn in our hospital. Totally 22 cases had normal liver and kidney function and no heart-brain-lung disease. There were 11 males and 11 females, the maximum age of 22 days and the minimum of 2 hours, an average of 13.4 days.