作者评价了17种抗血吸虫药物对小鼠感染曼氏血吸虫的化学预防作用。在动物感染前3小时,除海蒽酮、羟氨喹分别按单剂量一次肌注80毫克/公斤体重和200毫克/公斤体重外,其余药物均采用皮下给药,每天1次,共5天,每天剂量相当于该药急性LD_(50) The authors evaluated the chemopreventive effects of 17 anti-schistosoma drugs on Schistosoma mansoni in mice. Three hours prior to the animal infection, all the drugs were subcutaneously administered once a day for 5 days, except that the sea anthrones and hydroxyquramod were inoculated intramuscularly with 80 mg / kg body weight and 200 mg / kg body weight in a single dose respectively , The daily dose equivalent to the drug acute LD_ (50)