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目的:探讨连续性静脉-静脉血液透析滤过(CVVH)对重症急性胰腺炎(SAP)并急性呼吸窘迫综合征患者的疗效。方法:2007年2月—2014年4月收治24例重症急性胰腺炎合并急性呼吸窘迫综合征患者随机分为对照组12例,治疗组12例。治疗组在对照组治疗基础上行CVVH 治疗,均采用中心静脉置管建立血管通路,采用普通肝素或低分子肝素抗凝,每天治疗时间8~12 h。观察患者行HRRT后生化指标、APACHEⅡ评分的变化以及临床转归。结果:与对照组比较,经CVVH治疗后,氧合指数、WBC、CRP、AST、ALP、Cr、BUN均显著降低(P<0.05);APACHEII 评分降低、住院天数缩短、治愈好转率均显著升高,具有统计学意义(P<0.05)。结论: CVVH可能是治疗重症急性胰腺炎(SAP)并急性呼吸窘迫综合征的一种有效的辅助治疗方法,能降低患者的病死率,提高治愈好转率。“,”Objective:Continuous venous blood dialysis (CVVH) on severe acute pancreatitis (SAP) and the curative effect of patients with acute respiratory distress syndrome. Methods:In April 2007 to February 2007, 24 cases of severe acute pancreatitis treated 12 cases with acute respiratory distress syndrome were randomly divided into control group and treatment group (12 cases. The treatment group treats in the foundation in the control group uplink CVVH therapy. Results:Compared with control group, after treatment with CVVH, oxygenation index, the WBC, CRP, AST, ALP, Cr and BUN were significantly lower (P<0.05) Conclusions:CVVH is the treatment of severe acute pancreatitis (SAP) and acute respiratory distress syndrome is an effective auxiliary treatment, can reduce the mortality of patients, improve the cure, the.