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目的：评价山海丹治疗冠心病伴高粘度血症的效果。方法：４５例冠心病并发高粘度血症病人（男性２８例，女性１７例；年龄６２±ｓ９ａ），用山海丹２．５ｇ，ｐｏ，ｔｉｄ，４ｗｋ为一个疗程。观察治疗前后临床症状、心电图及血液流变学的改善情况。结果：主要临床症状胸闷、胸痛、心悸、乏力的总有效率分别为９１％，８２％，５６％，９２％；心电图恢复正常的总有效率达６２％；血粘度显著降低（Ｐ＜０．０１）。结论：山海丹是治疗冠心病伴高粘度血症的有效药物。
Objective: To evaluate the efficacy of Shanhaidan in the treatment of coronary heart disease with hyperviscosity. Methods: Forty-five patients with coronary heart disease complicated with hyperviscosity (28 males and 17 females; age 62±s9a) were treated with Shanhaidan 2.5g, po, tid and 4wk for one course of treatment. Observe the improvement of clinical symptoms, electrocardiogram, and hemorheology before and after treatment. Results: The main clinical symptoms of chest tightness, chest pain, palpitations, fatigue, the total effective rate were 91%, 82%, 56%, 92%; ECG returned to normal total effective rate of 62%; blood viscosity was significantly reduced (P <0 .01). Conclusion: Shanhaidan is an effective drug for the treatment of coronary heart disease with hyperviscosity.