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异名 Enkaid 化学名 (±)-2′-[2-(1-甲基-2-哌啶基)乙基]-对甲氧苯甲酰基苯胺盐酸盐药效分类抗心律失常药开发单位 (美)Bristol-Myers Co 上市厂商 (美)Bristol-Myers Co 1987年首次上市药理本品属IC类抗心律失常新药。通过阻断快反应Na~+内流而降低各种动物标本动作电位去极化时的最大上升速度(V_(max)),该作用呈剂量依赖性。本品是I类抗心律失常药物中降低V_(max)及延长速度依赖的动作电位回复时间最大的药物之一,对快Na~+流的阻断作用与氟卡胺或劳卡胺类似。本品还能减小离体组织标本动作电位幅
Synonyms Enkaid Chemical Name (±) -2 ’- [2- (1-methyl-2-piperidyl) ethyl] -parabenzoyl aniline hydrochloride Pharmacodynamic Category Anti-arrhythmic drug development unit (US) Bristol-Myers Co listed companies (the United States) Bristol-Myers Co 1987 debut Pharmacology This product is an IC anti-arrhythmic drug. By blocking the rapid reaction of Na ~ + influx and various animal specimens to reduce the action potential depolarization maximum rate of rise (V_ (max)), the dose-dependent manner. This product is one of the class I antiarrhythmic drugs to reduce the V_ (max) and prolongation of the speed-dependent action potential response time of the drug, the fast Na ~ + flow blocking effect and flecainide or rancar amine. This product can reduce the action potential amplitude of isolated tissue specimens