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目的比较单纯使用抗生素和痰热清联合抗生素治疗脑外术后肺部感染的效果。方法观察组74例,每天用痰热清注射液静脉滴注,同时静脉滴注头孢二代或三代抗生素进行抗感染治疗,如果患者有过敏反应改用奎诺酮类,对照组52例仅用头孢二代或三代抗生素进行治疗。比较两组患者临床感染的疗效和不良反应。结果观察组总有效率明显高于对照组,观察组肺部感染发生率20%,对照组肺部感染发生率39.1%;观察组死亡率11.9%,对照组死亡率26.9%。两组治疗效果比较结果均具有差异性(P<0.05)。结论痰热清联合抗生素在治疗脑外术后发生肺部感染中,效果明显好于单纯应用抗生素治疗,患者的感染发生率和死亡率明显低于仅用抗生素组。应用痰热清注射液治疗脑外术后肺部感染安全有效、副作用很小,具有推广价值,是一种较好的抗菌消炎中药。
Objective To compare the effect of antibiotics alone and Tanreqing combined with antibiotics in the treatment of pulmonary infection after cerebral surgery. Methods 74 cases of observation group were treated with intravenous infusion of phlegm-heat injection daily, while intravenous infusion of cephalosporin second or third generation antibiotics for anti-infective treatment, if patients with allergic reactions to quinolones, the control group of 52 patients Second or third generation cephalosporin antibiotics for treatment. The efficacy and adverse reactions of clinical infection in two groups were compared. Results The total effective rate in the observation group was significantly higher than that in the control group. The incidence of pulmonary infection was 20% in the observation group and 39.1% in the control group. The mortality rate in the observation group and the control group was 11.9% and 26.9%, respectively. The results of the two groups showed significant differences (P <0.05). Conclusion Tanreqing combined antibiotics in the treatment of pulmonary infection occurred after surgery, the effect was significantly better than the simple antibiotic treatment, the incidence of infection and mortality was significantly lower than the antibiotic group. The application Tanreqing injection in the treatment of pulmonary infection after brain surgery safe and effective, with little side effects, with the promotion of value, is a good antibacterial anti-inflammatory medicine.