论文部分内容阅读
目的 :总结原发性胃肠道恶性淋巴瘤的有效诊治方法。 方法 :对 6 6例原发性胃肠道恶性淋巴瘤的临床资料做回顾性分析。 结果 :6 6例患者均行手术探查 ,其中胃恶性淋巴瘤 2 3例 ,术前确诊 14例 ,均为胃镜下活检确诊 ;小肠淋巴瘤 19例 ,术前确诊 4例 ,为 CT或 B超引导下穿刺活检确诊 ;结肠淋巴瘤 2 4例 ,术前确诊 10例 ,均为肠镜下活检确诊。共 5 2例获得随访 ,其中胃恶性淋巴瘤术后 5年生存率为 47% ,小肠为 5 7.9% ,结肠为 45 .8%。病理类型均为非何杰金氏淋巴瘤 ,其中 B细胞型 40例 ,T细胞型 14例。 5 2例行辅助 COAP化疗 ,总有效率 92 .6 %。 结论 :1内窥镜下活检和 CT或 B超引导下活检最具确诊价值 ,X线检查有辅助诊断价值。 2手术治疗和化疗同等重要 ,免疫组化分型可作为判断预后的指标。
Objective: To summarize the effective diagnosis and treatment of primary gastrointestinal malignant lymphoma. Methods: The clinical data of 66 cases of primary gastrointestinal malignant lymphoma were analyzed retrospectively. Results: Sixty-six patients underwent surgical exploration, including 23 cases of gastric malignant lymphoma and 14 cases diagnosed preoperatively under biopsy. Among them, 19 cases were small intestinal lymphoma and 4 cases were diagnosed preoperatively as CT or B- Guided biopsy needle puncture; colon lymphoma 24 cases, 10 cases were diagnosed preoperatively, all confirmed by enteroscopy biopsy. A total of 52 cases were followed up. The 5-year survival rate of gastric malignant lymphoma was 47%, the small intestine was 5 7.9% and the colon was 45.8%. Pathological types are non-Hodgkin’s lymphoma, of which 40 cases of B cell type, T cell type in 14 cases. 5 2 routine adjuvant COAP chemotherapy, the total effective rate 92.6%. Conclusions: 1 Biopsy under endoscopy and CT or B-guided biopsy of the most diagnostic value, X-ray examination has diagnostic value. 2 surgical treatment and chemotherapy are equally important, immunohistochemical typing can be used as an indicator of prognosis.