Circadian rhythms have a period of ?24 h and are manifested in almost all living organisms[1].The discov-ery of the molecular genetic mechanisms underlying circadian rhythmicity was one of the most exciting and inspiring chapters in the history of biology and won the Nobel Prize in Physiology or Medicine in 2017[2].Equally exciting and inspiring was the discovery that the hypotha-lamic suprachiasmatic nucleus(SCN)is involved in orchestrating the daily rhythmic activity of physiology,metabolism,and behavior in mammals[3].