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目的:探讨超声雾化吸入野菊花注射液佐治婴幼儿支气管肺炎的临床疗效。方法:将137例婴幼儿支气管肺炎患儿随机分为治疗组69例和对照组68例,两组均给予常规综合治疗,治疗组在常规综合治疗基础上超声雾化吸入野菊花注射液,对照组在常规综合治疗基础上超声雾化吸入灭菌蒸馏水。治疗过程中观察患儿发热、咳嗽、喘息、气促及肺部干湿啰音消失情况,治疗前及治疗后第3天监测血常规和CRP水平。结果:治疗组患儿发热、咳嗽、喘息及肺部体征消失时间均早于对照组(P<0.05),平均住院时间少于对照组[(13.7±3.7)d vs(16.2±4.5)d,P<0.05],白细胞计数及CRP水平均较治疗前降低(P<0.05),且均低于对照组(P<0.05),总有效率高于对照组(89.9%vs 67.6%,P<0.05)。结论:超声雾化吸入野菊花注射液佐治婴幼儿支气管肺炎具有明显疗效。
Objective: To investigate the clinical efficacy of ultrasonic atomization inhalation of Chrysanthemum injection for treating infantile bronchial pneumonia. Methods: A total of 137 infants and children with bronchial pneumonia were randomly divided into treatment group (n = 69) and control group (n = 68). Both groups were given conventional comprehensive treatment. The treatment group was treated with inhalation of Chrysanthemum injection on the basis of conventional comprehensive treatment, Group on the basis of conventional comprehensive treatment of ultrasonic inhalation sterilization distilled water. During treatment, children were observed for fever, cough, wheezing, shortness of breath, and disappearance of dry and wet lung rales. Blood and CRP levels were monitored before treatment and on the 3rd day after treatment. Results: The onset of fever, cough, wheezing and lung signs in treatment group were earlier than those in control group (P <0.05), and the average hospital stay was less than that in control group [(13.7 ± 3.7) d vs (16.2 ± 4.5) days, P <0.05]. The white blood cell count and CRP level were lower than those before treatment (P <0.05), and were lower than those in the control group (P <0.05). The total effective rate was higher than that of the control group (89.9% vs 67.6%, P <0.05) ). Conclusion: Ultrasound nebulization Chrysanthemum injection adjuvant treatment of bronchial pneumonia in infants and young children has a significant effect.