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我们利用人结肠癌SW480裸鼠移植瘤模型,研究促胃液素及丙谷胺对人结肠癌裸鼠移植瘤生长的影响,旨在为结肠癌的内分泌治疗提供实验依据.1 材料和方法1.1 材料 人结肠癌细胞株SW480(美国纪念斯隆—凯特林癌症中心制备,重庆医科大学病理生理教研室提供),
We used human colon cancer SW480 xenograft tumor model to study the effects of gastrin and proglumide on the growth of human colon cancer xenografts in nude mice, aiming to provide experimental basis for endocrine therapy of colon cancer. 1 Materials and methods 1.1 Materials human colon cancer cell line SW480 (prepared by Memorial Sloan-Kettering Cancer Center of the United States, provided by the Department of Pathophysiology, Chongqing Medical University),