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目的：探讨抗巨噬细胞抗体与肾脏病的关系。方法：应用葡萄球菌蛋白Ａ（ＳＰＡ）花环试验检测慢性肾小球肾炎、过敏性紫癜肾炎和肾盂肾炎患者血清抗巨噬细胞抗体含量（ＳＰＡ花环形成率）。结果：慢性肾小球肾炎、过敏性紫癜肾炎和复发性肾盂肾炎患者血清抗巨噬细胞抗体含量显著高于对照组。结论：抗巨噬细胞抗体所致的巨噬细胞功能障碍和免疫功能紊乱可能参与慢性肾小球肾炎、过敏性紫癜肾炎和复发性肾盂肾炎的疾病过程，血清抗巨噬细胞抗体检测对病情判断有参考价值
Objective: To investigate the relationship between anti-macrophage antibodies and renal disease. Methods: Serum anti-macrophage antibody levels (SPA rosette formation rate) in patients with chronic glomerulonephritis, Henoch-Schonlein purpura nephritis and pyelonephritis were measured using the Staphylococcus aureus (SPA) garland test. Results: The levels of serum anti-macrophage antibodies in patients with chronic glomerulonephritis, allergic purpura nephritis and recurrent pyelonephritis were significantly higher than those in the control group. Conclusion: Anti-macrophage antibody-induced macrophage dysfunction and immune dysfunction may be involved in the pathogenesis of chronic glomerulonephritis, Henoch-Schonlein purpura nephritis and recurrent pyelonephritis, and the detection of serum anti-macrophage antibodies A reference value