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目的: 评价脑诱发电位(EP) 诊断亚临床型肝性脑病(SHE) 的价值.方法: 对48 例肝炎后肝硬化患者进行三种EP检查, 并追踪1年观察临床肝性脑病(HE) 出现情况.结果: 三种脑诱发电位总异常26例(54％ ),其中听觉诱发电位 (BAEP) 异常18例 (38％ )、视觉诱发电位(VEP) 异常3 例(6％ )、体感诱发电位 (SEP) 异常10 例 (21％ ), 以BAEP异常率最高.追踪观察1 年的29例患者中, 15例EP异常者出现HE11 例 (73％ ), 无EP异常14例中, 出现HE4 例(28％ ) (P＜ 0.05).结论: 揭示BAEP对诊断SHE最敏感, 同时三种EP检查可提高SHE的检出率, 检测SHE有助于预测HE的发生有临床价值“,”Objective: To explore the value of evoked potentials (EP) in early detection of subclinical hepatic encephalopathy (SHE) Methods: Evoked potentials were performed in 48 patients with liver cirrhosis and patients were followed up for one year for development of overt hepatic encephalopathy (HE) Results: Evoked potentials were abnormal in 26(54%) patients, 18(38%) with abnormal brainstem evoked potential (BAEP) 3(6%) with abnormal, visual evoked potential (VEP) in 3(6%) and 10(21%) with abnormal somatosensory evoked potential(SEP) Among 29 cases followed up for one year, 11 of 15(73%) with abnormal evoked potential developed HE, compared to 4 of 14 (28%)with normal evoked potential ( P <0 05) Conclusions: There was added advantage of performing three kinds of EP at the same time for improved detection of SHE, which helps to predict the development of HE