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综述了丙硫菌唑及其中间体的合成方法,总结出四条常用合成路线,并对各条路线进行初步的比较和评价。笔者认为,路线B以1-乙酰基-1-氯环丙烷为起始原料合成丙硫菌唑的方法值得关注。
The synthetic methods of prothioconazole and its intermediates were summarized, four common synthetic routes were summarized, and the preliminary comparison and evaluation of each route were made. The author believes that Route B to 1-acetyl-1-chlorocyclopropane as the starting material for the synthesis of prothioconazole method of concern.