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胃癌的发病率及死亡率虽逐渐下降,但仍威胁健康。目前诊断胃癌的金标准为胃镜活检,但存在技术要求高、费用贵且患者痛苦等问题,尚不能作为普查手段。血清学检测具有简便、快速、非侵入性、标本方便获得、成本较低和便于动态监测等特点,对筛查胃癌及其癌前病变有一定优势。现综合近年国外最新研究进展,对常用的胃癌筛查血清学指标做一介绍,并对最新应用方法做简要综述。
The incidence of gastric cancer and mortality, although gradually decreased, but still threatening health. The current gold standard for the diagnosis of gastric cancer gastroscopy biopsy, but there are high technical requirements, expensive and suffering patients and other issues, but not as a means of census. Serological detection is simple, rapid, non-invasive, convenient access to specimens, lower cost and easy to dynamic monitoring, etc., for screening gastric cancer and precancerous lesions have some advantages. Based on the latest research progress abroad in recent years, this paper introduces the commonly used serological markers of gastric cancer screening and briefly reviews the latest application methods.