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目的：了解清洁伤口术预防性使用抗生素的情况，评价其使用的合理性，方法：回顾性调查广西医科大学附属一院耳鼻喉科、眼科、整形科共３３６７例清洁伤口术的抗生素的使用情况。结果：９９．１％的病例术后常规应用抗生素，经统计学处理发现用药组与不用药组术后伤口感染率无显著性差异（术前应用抗生素达３天或３天以上的占本组例数的２０．４９％（６８４例），而用１～２天的也有５．６３％（１７９例）。术后联合应用３种抗生素预防感染达３５６例，用３种的也有２０例，分别占本组例数的１０．６７％和０．６０％。结论：围术期预防用药主要采用杀菌性抗生素是合理的，但存在预防性用药率过高、术前用药时间过长及不必要的联合用药等问题。眼科术后常规地全身性应用氨基糖甙类抗生素预防感染应是不合理的
OBJECTIVE: To understand the prophylactic use of antibiotics in clean wounds and to evaluate the rationality of its use. Methods: A retrospective survey was conducted on the use of antibiotics in 3367 cases of otolaryngology, ophthalmology and orthopedics in the First Affiliated Hospital of Guangxi Medical University . Results: 99.1% of the patients were routinely treated with antibiotics. The statistical analysis showed no significant difference in postoperative wound infection rates between the two groups (preoperative antibiotics for 3 days or more than 3 days) The number of cases was 20.49% (684 cases), while the use of 1 to 2 days were also 5.63% (179 cases) .Postoperative combination of three antibiotics to prevent infection up to 356 cases, with 3 kinds of 20 cases, Respectively, accounting for 10.67% and 0.60% in this group.Conclusion: It is reasonable to use bactericidal antibiotics mainly for perioperative prophylaxis, but there is a high rate of prophylactic drug use, too long preoperative medication time and no The necessary combination of medication and other issues.Ophthalmology general conventional aminoglycoside antibiotics to prevent infection should be unreasonable