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遗传性肾炎(hereditary nephfitis)的临床特点,为反复发作性血尿、慢性进行性肾功能衰竭、部分患者可合并神经性耳聋及眼部疾患。作者在遗传病调查中,发现连续三代共13人发病(见家系图), 病例介绍: 1:先证者Ⅳ_(10),8岁。3岁时因全身浮肿就医,拟诊“肾炎”,给于对症治疗,愈后出院。此后,常于感冒、劳累、受寒后一天左右出现肉眼或镜下血尿(+~++++)、浮肿,而多次住院治疗。其大哥Ⅳ_8,亦于3岁开始反复出现血尿(+~肉眼)、蛋白尿(+~++),至10岁时因尿毒症治疗无效死亡。大舅Ⅲ_7,l岁时出现血尿,以后反复发作至34岁时,
Hereditary nephritis (hereditary nephfitis) clinical features, recurrent hematuria, chronic progressive renal failure, some patients may be combined with neurological deafness and eye diseases. The author in the genetic disease survey, found that a total of 13 consecutive three generations of onset (see family tree), case description: 1: proband IV_ (10), 8 years old. 3 years old due to systemic edema, medical consultation, “nephritis” for symptomatic treatment, the more discharged. Since then, often in a cold, tired, about one day after cold appeared naked eye or microscopic hematuria (+ ~ ++++), edema, and multiple hospitalizations. The older brother Ⅳ_8 also began to hematuria (+ ~ macroscopic) and proteinuria (+ ~ ++) at the age of 3, and died of uremia by the age of 10. Uncle Ⅲ_7, hematuria at age l, after repeated attacks to 34 years old,