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癌症外科的传统概念,认为癌症是单一细胞突变的局部病,体细胞一旦突变成为癌细胞,它是进行性的和不可逆转的,癌细胞先在局部离心性生长,继而向区域淋巴结或血行转移扩散。为此,在癌症广泛扩散前,用外科手段切除机体最后一个癌细胞,就能治愈癌症。1894年Halsted据此首先设计了标化的乳癌根治术,其手术原则是整块地切除癌灶的器官及其所属淋巴结,作者报告232例手术结果,3年生存率32.3%,5年生存率29.8%,这在当
The traditional concept of cancer surgery believes that cancer is a local disease of a single cell mutation. Once a somatic cell has been mutated into a cancer cell, it is progressive and irreversible. The cancer cells first grow in a local centrifugal state and then migrate to regional lymph nodes or blood. diffusion. For this reason, cancer can be cured by surgically removing the last cancer cell before widespread cancer spread. In 1894, Halsted first designed a standardized breast cancer radical resection. The principle of surgery was to remove the entire lesion organ and its associated lymph nodes. The authors reported 232 cases of surgical outcomes. The three-year survival rate was 32.3%, and the 5-year survival rate was. 29.8%, this is in