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目的 :总结连续性肾脏替代 (CRRT)在抢救 32例重症急肾衰 (ARF)过程中的临床资料 ,探讨其与一般血液透析比较的优势和治疗的意义 ,进一步提高重症急肾衰的存活率。方法 :在患者床旁建立血管通路 ,利用两个血泵 ,一个控制超滤量 ,另个补置换液。在CRRT的开始 ,中间和结束后 ,进行临床症状、生化和氧分压的总结与检测。结果 :32例患者经过治疗 ,病情都得到一定程度缓解 ,有 19例存活 ,存活率达 5 9%。结论 :CRRT血液动力学稳定 ,能改善组织的氧代谢 ,清除炎症介质 ,使尿素氮平稳下降 ,有利于重症ARF的恢复。
OBJECTIVE: To summarize the clinical data of CRRT in the rescue of 32 patients with severe acute renal failure (ARF), and to explore its advantages compared with general hemodialysis and the significance of treatment, and to further improve the survival rate of severe acute renal failure . Methods: Vascular access was established at the patient’s bed, using two blood pumps, one to control the amount of ultrafiltration and the other to replace fluid. Clinical symptoms, biochemical and partial pressure of oxygen were summarized and tested at the beginning, middle, and end of CRRT. Results: Thirty-two patients were treated and the disease was relieved to a certain degree. Nineteen patients survived and the survival rate was 59%. Conclusion: The hemodynamic stability of CRRT can improve the oxygen metabolism of tissues, clear the inflammatory mediators, and make the blood urea nitrogen stable decline, which is good for the recovery of severe ARF.