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目的分析铜陵某地村民“硬皮病样”改变的病因。方法运用现场流行病学调查及其病因推断原则进行分析。结果 14例患者临床呈硬皮病倾向,无传染性、无家族聚集性或遗传性;患者的地区分布在瓠子冲河两侧;发病时间分布与某些企业生产废水排放时间有关联;患者有养鱼、挖藕和稻田劳作史,村民不再接触河沟污水后无新发病例出现。结论 14例“硬皮病样”病例与接触污染河水有关,具体致病因素有待于进一步查验。
Objective To analyze the causes of the change of “scleroderma-like” villagers in a certain area in Tongling. Methods The field epidemiological survey and its etiological inference principle were used to analyze. Results The clinical manifestations of scleroderma in 14 patients were noninfectious, familial aggregation or hereditary. The distribution of the patients was on both sides of Chizhen River. The distribution of the incidence was related to the discharge time of some production wastewater. The patients had Fish farming, dig lotus root and paddy labor history, the villagers no longer contact the river ditch sewage no new cases. Conclusions 14 cases of “scleroderma-like” cases are related to exposure to polluted river water, and the specific risk factors need to be further investigated.