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目的探讨地佐辛应用于无痛胃肠镜检查中的临床疗效。方法 300例行无痛胃肠镜检查的患者,随机分为对照组和观察组,各150例。对照组给予丙泊酚麻醉,观察组给予丙泊酚与地佐辛进行术前麻醉。比较两组患者术前及术后30 min的收缩压(SBP)、舒张压(DBP)、心率(HR)、呼吸频率(RR)、血氧饱和度(Sp O2)的变化及临床不良反应。结果两组患者术前与术后30 min的SBP、DBP、HR、RR、Sp O2比较差异无统计学意义(P>0.05);观察组不良反应发生率为4.0%,低于对照组的10.0%(P<0.05)。结论地佐辛在无痛胃肠镜检查过程中麻醉效果好,不良反应发生率低,且安全、可靠,可供临床参考。
Objective To investigate the clinical efficacy of dezocine in painless gastrointestinal endoscopy. Methods 300 cases of painless gastrointestinal endoscopy were randomly divided into control group and observation group, 150 cases each. The control group was given propofol anesthesia, and the observation group was given propofol and dezocine for preoperative anesthesia. The changes of SBP, DBP, HR, respiratory rate (RR) and oxygen saturation (Sp O2) and clinical adverse reactions were compared between the two groups before and 30 minutes after operation. Results There was no significant difference in SBP, DBP, HR, RR and Sp O2 between the two groups before and 30 minutes after operation (P> 0.05). The incidence of adverse reactions in the observation group was 4.0%, which was lower than that in the control group % (P <0.05). Conclusion Dezocine has a good anesthetic effect and a low incidence of adverse reactions during the painless gastrointestinal endoscopy and is safe and reliable for clinical reference.