论文部分内容阅读
作者在40例急性白血病、10例慢性粒细胞白血病病人中发现,当并发肺炎及化脓性皮炎时,血清溶菌酶明显下降(无感染时血清溶菌酶浓度为4.5微克/毫升,感染时为2.7微克/毫升,有口腔粘膜溃疡和口腔炎的白血病病人,其唾液中溶菌酶的含量也下降2～3倍(从37.5降至13.1微克/毫升。血清和唾液中溶菌酶的减少,可能由于药物引起粒细胞减少时,分泌细胞也同时减少所造成。这也是病人感染的原因之一。据上述材料,作者在白血病病人的综合治疗中,应用了晶体溶菌酶来预防和治疗各种感染。有口腔粘膜坏死性溃疡的10例急白和10例慢粒,用1％溶菌酶溶液嗽口,每天饭后3～4次,能使炎症减轻。随着病情好转,唾液中溶菌酶的滴度也恢复正常。为了预防急白病人在粒细胞减少期间并发肺炎,采用预防性吸入疗法,其药物成份,除抗菌素和解痉药外,还有溶菌酶(1毫克/毫升),每天吸入2次。
In 40 patients with acute leukemia and 10 patients with chronic myeloid leukemia, the authors found that serum lysozyme was significantly decreased in patients with pneumonia and suppurative dermatitis (serum lysozyme concentration of 4.5 μg / ml without infection and 2.7 μg / Ml, patients with leukemia with oral mucosal ulceration and stomatitis also have a 2 to 3 fold decrease in lysozyme levels in their saliva (from 37.5 to 13.1 μg / mL.) The reduction of lysozyme in serum and saliva may be due to the drug This is also one of the reasons for the patient’s infection.According to the above materials, the author in the comprehensive treatment of leukemia patients, the application of crystal lysozyme to prevent and treat various infections .Oral Mucosal necrotizing ulcer in 10 cases of acute white and 10 cases of slow granules, mouthwash with 1% lysozyme solution, 3 to 4 times a day after meals, can reduce the inflammation. With the condition improved, the titer of lysozyme in saliva Return to normal .In order to prevent acute white patients during neutropenia complicated by pneumonia, the use of prophylactic inhalation therapy, the drug ingredients, in addition to antibiotics and antispasmodics, there are lysozyme (1 mg / ml), every day 2 times.