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目的 探讨2型糖尿病患者并发高甘油三酯血症与急性胰腺炎发生的关系,以指导糖尿病患者急性胰腺炎的预防和治疗.方法 选取2013年1月-2016年12月榆林市第一医院收治的2型糖尿病并发急性胰腺炎患者46例为试验组,另选取本院同期收治的单纯2型糖尿病患者52例为对照组.记录患者的年龄、性别、糖尿病病程、身高、体质量、腹围、吸烟、饮酒、胆结石、高血压、血糖、血脂情况[TC、TG、HDL-C、LDL-C].检测患者糖尿病相关并发症的发生情况.计数资料2组间比较采用 χ2检验,计量资料2组间比较采用t检验;采用logistic回归进行多因素分析.结果 2组患者在年龄、性别构成、身高、体质量、腹围、吸烟饮酒习惯、高血压、胆结石、糖尿病病程等方面的差异无统计学意义(P值均>0.05);试验组患者的TC、TG、LDL-C水平均显著高于对照组,差异均有统计学意义(t值分别为5.122、4.127、3.524,P值分别为<0.01、<0.01、0.012),对照组患者的HDL-C水平显著高于试验组,差异统计学意义(t=2.231,P=0.037);试验组患者的糖尿病微血管病变(糖尿病视网膜病变、糖尿病慢性肾病)发病率显著高于对照组(χ2=92.126,P0. 05). The study group had significantly higher levels of TC,TG,and LDL - C than the control group (t = 5. 122,4. 127,and 3. 524, P < 0. 01,< 0. 01,and = 0. 012),while the control group had a significantly higher level of HDL - C than the study group (t = 2. 231, P = 0. 037). The study group had a significantly higher incidence rate of diabetic microangiopathy (diabetic retinopathy and chronic diabetic nephropathy)than the control group (χ2 = 92. 126,P < 0. 01). The multivariate analysis showed that compared with those with a normal TG level,the type 2 diabetic patients with a high TG level had a risk of acute pancreatitis increased by 47. 6% (odds ratio [OR]= 1. 476,P =0. 031),and the type 2 diabetic patients with a high LDL - C level had a risk of acute pancreatitis increased by 48. 7% (OR = 1. 487,P =0. 045). Conclusion Blood lipids should be measured for patients with type 2 diabetes,and blood glucose and blood lipid levels should be actively controlled for patients with type 2 diabetes complicated by hypertriglyceridemia,in order to reduce the incidence rate of acute pan-creatitis.