三吡荼啶化学名为2-四氢吡咯-7-氯-10[3′,5′—双(四氢吡咯-1-甲基)-4-羟基苯基]氨基苯肼(b)15-萘啶,抗疟新药咯萘啶的类似物。本文报道了其在鼠疟和猴疟模型上的抗疟作用。三吡萘啶和咯萘啶治疗伯氏疟原虫ANKA株的ED_(50)分别为2.63mg/(kg·d)×4和0.85mg/(kg·d)×4。三吡萘啶与氯喹、哌喹和 Tetrapyradine has the chemical name of 2-tetrahydropyrrole-7-chloro-10 [3 ’, 5’-bis (tetrahydropyrrole- 1 -methyl) -4-hydroxyphenyl] aminophenylhydrazine (b) 15 - naphthyridine, an antimalarial drug pyronaridine analogues. This article reports its anti-malarial effects on murine and monkey malaria models. The ED_ (50) of tripyronaphthyridine and pyronaridine treatment of ANKA strain of Plasmodium berghei were 2.63 mg / (kg · d) × 4 and 0.85 mg / (kg · d) × 4, respectively. Triphenylnaphthalene with chloroquine, piperacillin and